Our goal is to inspire innovative development of novel diagnostic tests that can provide proof of concept through limited testing on provided samples. Competitive solutions to this challenge shall be sensitive and specific for CWD, producing timely and repeatable results on samples easily obtained from live deer. Competitive solutions will also be cost-effective and readily manufactured. The ideal solutions to this challenge are diagnostic tests that could be eligible for approval as an official Chronic Wasting Disease test by the Administrator of the Animal and Plant Health Inspection Service (APHIS).